Browsing by Author "Constantinidou, Anastasia"
Now showing items 1-20 of 72
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Article
Advanced aggressive fibromatosis: Effective palliation with chemotherapy
Constantinidou, Anastasia; Jones, Robin Lewis; Scurr, Michelle R.; Al-Muderis, Omar; Judson, Ian Robert (2011)Background. Aggressive fibromatosis (AF) is a locally invasive proliferative disease. The mainstay of treatment is surgery. Chemotherapy may be considered in inoperable AF following failure of hormonal therapy and/or NSAIDs. ...
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Article
Advanced soft-tissue sarcoma and treatment options: Critical appraisal of trabectedin
Desar, Ingrid M. E.; Constantinidou, Anastasia; Kaal, Suzanne E. J.; Jones, Robin Lewis; Graaf, W. T. A. van der (2016)Soft-tissue sarcomas (STS) are a heterogeneous group of rare solid tumors of mesenchymal origin. This paper reviews the current status of systemic treatment in advanced and metastatic soft tissue sarcomas, with an emphasis ...
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Article
Assessing response to chemotherapy in metastatic melanoma with FDG PET: Early experience
Hofman, Michael S.; Constantinidou, Anastasia; Acland, Katharine M.; Healy, Ciaran; Harries, Mark; O'Doherty, M. (2007)The management of metastatic melanoma remains challenging with only modest response rates to chemotherapy but the need to identify the best re-staging techniques remains paramount. This study evaluates our early experience ...
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Article
Beyond triple-negative breast cancer: The need to define new subtypes
Constantinidou, Anastasia; Jones, Robin Lewis; Reis-Filho, J. S. (2010)Advances in the systemic treatment of early breast cancer have led to significant improvements in survival for patients with hormone receptor- and/or HER2-positive disease. In recent years, interest has focused on tumors ...
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Article
Cervical Cancer Screening Programs in Europe: The Transition Towards HPV Vaccination and Population-Based HPV Testing
Chrysostomou, Andreas C.; Stylianou, Dora C.; Constantinidou, Anastasia; Kostrikis, Leondios G. (2018)Cervical cancer is the fourth most frequently occurring cancer in women around the world and can affect them during their reproductive years. Since the development of the Papanicolaou (Pap) test, screening has been essential ...
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Article
Cervical Cancer Screening Programs in Europe: The Transition Towards HPV Vaccination and Population-Based HPV Testing
Chrysostomou, Andreas C.; Stylianou, Dora C.; Constantinidou, Anastasia; Kostrikis, Leondios G. (2018)Cervical cancer is the fourth most frequently occurring cancer in women around the world and can affect them during their reproductive years. Since the development of the Papanicolaou (Pap) test, screening has been essential ...
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Article
Chemotherapy in clear cell sarcoma
Jones, Robin Lewis; Constantinidou, Anastasia; Thway, K.; Ashley, Sue; Scurr, Michelle R.; Al-Muderis, Omar; Fisher, Cyril; Antonescu, Cristina R.; D'Adamo, David R.; Keohan, Mary Louise; Maki, Robert G.; Judson, Ian Robert (2011)Clear cell sarcoma is a rare translocation-related sarcoma. There have been few studies documenting the response rate and progression-free survival in clear cell sarcoma patients treated with palliative chemotherapy. The ...
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Article
Clinical activity and tolerability of a 14-day infusional ifosfamide schedule in soft-tissue sarcoma
Martin-Liberal, Juan; Alam, Salma; Constantinidou, Anastasia; Fisher, Cyril; Khabra, Komel; Messiou, Christina; Olmos, David; Mitchell, Scott; Al-Muderis, Omar; Miah, Aisha; Linch, Mark; Jones, Robin Lewis; Scurr, Michelle R.; Judson, Ian Robert; Benson, Charlotte (2013)Background. Soft-tissue sarcomas (STS) are a heterogeneous group of diseases with lack of effective treatments in most cases. Previous data suggest that continuous infusional ifosfamide regimens might improve cytotoxicity ...
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Book Chapter
Clinical presentation of desmoid tumors
Constantinidou, Anastasia; Scurr, Michelle R.; Judson, Ian Robert; Litchman, C. (Springer, 2012)Desmoid tumors (DT) constitute a rare fibroblastic proliferative disease. They present sporadically or as a manifestation of a hereditary syndrome such as Familial Adenomatous Polyposis (FAP). Despite the absence of ...
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Article
Clinical trial design methodologies for advanced sarcoma therapy
Petek, B. J.; Pollack, S. M.; Constantinidou, Anastasia; Jones, Robin Lewis (2015)Sarcomas are rare and heterogeneous mesenchymal tumors affecting connective tissue. For many years, doxorubicin-based chemotherapy has been the main systemic therapy option for patients with metastatic soft tissue sarcoma. ...
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Article
Comparative Immunohistochemical Study of Ras-P21 Oncoprotein in Adenomatous Hyperplasia and Adenocarcinoma of the Prostate-Gland
Agnantis, Niki J.; Constantinidou, Anastasia; Papaevagelou, M.; Apostolikas, N. (1994)The present study assessed the immunohistochemical expression of ras p21 oncoprotein in 41 cases of benign and cancerous lesions of the prostate gland and correlated p21 expression with survival of patients operated for ...
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Article
Comprehensive surgical treatment as the mainstay of management in retroperitoneal sarcomas: Retrospective study from two non-sarcoma specialist centers
Petrou, A.; Constantinidou, Anastasia; Kontos, Michael; Papalampros, A.; Moris, Demetrios; Bakoyiannis, Chris; Neofytou, K.; Kourounis, George; Felekouras, Evagelos (2017)Background/Aim: Complete resection, surgical expertise and individualization of patient management in comprehensive oncology centres result in better clinical outcomes in patients presenting with retroperitoneal sarcomas. ...
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Article
Conventional anthracycline-based chemotherapy has limited efficacy in solitary fibrous tumour
Constantinidou, Anastasia; Jones, Robin Lewis; Olmos, David; Thway, K.; Fisher, Cyril; Al-Muderis, Omar; Judson, Ian Robert (2012)
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Article
Current management of stage I testicular non-seminomatous germ cell tumours
Pectasides, Dimitrios; Pectasides, E.; Constantinidou, Anastasia; Aravantinos, Gerasimos (2009)Testicular germ cell tumors represent the most common malignancies in young males between the ages of 15 and 35; 50% of those with non-seminomatous germ cell tumors (NSGCT) have clinical stage I at diagnosis. Predictors ...
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Book
Desmoid Tumour: clinical presentations.
Constantinidou, Anastasia; Scurr, Michelle R.; Judson, Ian Robert (Springer Science, 2010)
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Article
Diagnosis, prognosis, and management of leiomyosarcoma: Recognition of anatomic variants
Bathan, Andrew J.; Constantinidou, Anastasia; Pollack, S. M.; Jones, Robin Lewis (2013)PURPOSE OF REVIEW: The purpose of this review is to present the most recent advances in the diagnosis of the more common leiomyosarcoma (LMS) anatomic variants, potentially useful prognostic markers that have recently been ...
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Article
Early assessment of MCV to predict clinical outcome in patients with advanced gastrointestinal stromal tumors (GIST) receiving imatinib.
Constantinidou, Anastasia; Krikelis, Dimitrios; Olmos, David; Scurr, Michelle R.; Jones, Robin Lewis; Ashley, Sue; Judson, Ian Robert (2012)
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Article
The efficacy of caffeine-potentiated chemotherapy in clear cell sarcoma
Jones, Robin Lewis; Constantinidou, Anastasia (2013)
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Article
Epigenetic modulation in well differentiated (WD) and dedifferentiated (DD) liposarcoma (LPS): a novel therapeutic approach
Constantinidou, Anastasia; Selfe, J.; Khin, T.; Popov, S.; Missiaglia, E.; Aladowicz, E.; Al-Saadi, R.; Olmos, David; Jones, Robin Lewis; Strauss, D. C.; Hayes, Alison J.; Graaf, W. T. A. van der; Judson, Ian Robert; Shipley, J. (2016)
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Article
The evolution of systemic therapy in sarcoma
Constantinidou, Anastasia; Pollack, S. M.; Loggers, Elizabeth; Rodler, E.; Jones, Robin Lewis (2013)Approximately 50% of patients with localized soft tissue sarcomas will develop recurrent disease after complete surgical resection, requiring alternative means of treatment. Conventional chemotherapy comprising of doxorubicin ...